TXNIP and Alzheimer disease: Among these, CPS1 is involved in ammoniac intake in the urea cycle [37], PTPRC is one of the microglial expressed gene [38], SARM1 is involved in axon degeneration, which a factor observed in AD [39], TXNIP is linked to neuroprotective function [40], ANKS1B regulates hippocampal synaptic transmission [41] and LANCL1 is required for normal neuronal function [42].