To clarify the role of JAK2/STAT3 signaling in glioma EMT and determine whether NC modulates JAK2/STAT3 signaling as a mechanism for inhibiting EMT in glioma cells, we used WP1066 to inhibit JAK2/STAT3 activity in U87 and LN18 glioma cells during exposure to TGF‐β1 for the induction of EMT. Here, TGFB1 is linked to central nervous system cancer.