Among the RNAs identified in AD‐model aggregates (Table 2), many encode proteins that are themselves enriched in AD aggregates: for example, HnRNP_A2/B1, clusterin/ApoJ, β‐crystallin A (CRYAB), SERCA_2/ATP2A2, GFAP, APOE, and Amyloid Precursor Protein/APP (Ayyadevara, Balasubramaniam, Parcon, et al., 2016). This evidence concerns the gene APOE and Alzheimer disease.