APOE and Alzheimer disease: Of the 38 loci that showed significant DNA read peaks in at least one pool (each p < 10‒5 that the reads actually came from a uniform distribution), 25 reached that threshold in AD vs. 28 in AMC tissue, and 26 in T98G cells carrying APOE3 vs. 30 in APOE4 cells (Table 1, Supplementary Table S1).