IL1B and type 2 diabetes mellitus: Our data, showing an increase in expression of IL-1β RNA in PBMCs and high WBC count in a-NSW, and a significant correlation of HbA1c with leukocyte IL-1β RNA expression, suggest a potential common underlying mechanism for these changes and confirm the chronic low-grade inflammation is a recognized key feature associated with the risk of T2D development [22] and its complications [23].