Despite the success of EGFR inhibitor treatment, questions on whether the benefits of continuing EGFR inhibitor treatment are temporary or long-term, how the overall survival is affected after EGFR inhibitor discontinuation, and what factors are correlated with overall survival in patients with metastatic stage III/IV NSCLC who receive hospice care remain unanswered. Here, EGFR is linked to non-small cell lung carcinoma.