IECC defines usual-type ECA as 0% to 50% of tumor cells harboring appreciable intracytoplasmic mucin.[7] Mucin-depleted usual-type ECA is 1 end of morphological lineage of usual-type ECA with no mucin in cytoplasm and may display mild to moderate nuclear atypia, which morphologically favors endometrioid-type differentiation. This evidence concerns the gene MUC5AC and neoplasm.