It has been reported that Ulinastatin can reduce the expression of Caspase-3 by inhibiting the release of inflammatory factors such as IL-6, thus playing a protective role in myocardial injury of sepsis.[11] Ulinastatin can also reduce TNF - α to inhibit inflammatory reaction and protect liver function after hepatectomy.[12] In addition, Ulinastatin can play an anti-inflammatory and improve immune function in patients with severe burns.[13]. This evidence concerns the gene TNF and Sepsis.