Palpable purpura, oral ulcers, leukopenia, thrombocytopenia, high titer fluorescent ANA with a homogenous pattern, anti-ds DNA positivity, and low serum complement in his evaluation met the “2015 ACR/SLICC Revised Criteria for Diagnosis of Systemic Lupus Erythematosus.” Here, BTG3 is linked to systemic lupus erythematosus.