While SPI1 was positively correlated (ρ = 0.69, p‐value = 0.033) with the age of the control cases, it was negatively correlated with the age of patients with TSC cortical tubers (ρ = −0.74, p‐value = 0.0064) (Figure 3A,B). This evidence concerns the gene SPI1 and tuberous sclerosis.