INS and Insulin resistance: First, although the fasting blood glucose level and glucose clearance during OGTT in the KD(72%) mice were similar to those in the NC group (Fig. 6a and b), the secretion of insulin was significantly higher in the KD(72%) mice (Fig. 6c and d), and the KD(72%) mice also had a higher HOMA-IR index and insulin resistance index (Fig. 6e and f).