Here SWIM implicated FOSL1 as a putative master regulator of a core of four master neurodevelopmental transcription factors (i.e., SOX2, SALL2, OLIG2, POU3F2), whose induction was demonstrated to be sufficient to reprogram fully differentiated glioblastoma cells into stem-like cells [125]. This evidence concerns the gene SOX2 and glioblastoma.