We noticed that let-7a-5p expression was negatively correlated with TNF-α (p = 0.0310; Fig. 2d), IL-1β (p = 0.0044; Fig. 2e), and IL-6 (p = 0.0495; Fig. 2f) in CRSwNP. Here, TNF is linked to chronic rhinosinusitis with nasal polyps.