FAN1 and hereditary disease: TRPM1 is located in human chromosome 15q13.3, a region associated with 15q13.3 microdeletion syndrome, which is a genetic disorder caused by the deletion of a ~1.5 megabase region from break-point 4 to break-point 5, comprising 7 genes: MTMR10; FAN1; TRPM1; MIR211; KLF13; OTUD7A; and CHRNA7 (OMIM #612001) [4].