In Cox proportional hazard model bivariable analysis including sex of caregivers, occupation of caregivers, test and treat strategies, weight for age, height for age, TB status, regimen type, CPT, CD4 count threshold level, level of adherence, WHO clinical staging, and OI status were having P value less than 0.25 for the occurrence of anemia and entered into the multivariable analysis. The gene discussed is CD4; the disease is anemia.