Moreover, we identified and constructed a 15 immune genes risk scores model for breast cancer through univariate and lasso regression analysis, including TSLP, IL17B, NR3C2, RAC2, SERPINA3, HSPA2, CD79A, UNC93B1, NFKBIE, SDC1, IFNG, IRF7, GALP, TNFRSF18 and ULBP1. This evidence concerns the gene SERPINA3 and breast cancer.