ACE and Hypoglycemia: Moreover, the intervention with the supportive care ‘bundle’ should encompass 1) optimization of volume and hemodynamic parameters, which in the case of type B aortic dissection patients means volume optimization before the procedure and blood pressure control; 2) limit of nephrotoxic drugs, such as aminoglycoside antibiotics, nonsteroidal anti-inflammatory agents, angiotensin-converting enzyme inhibitor (ACEI), and angiotensin receptor blockers (ARBs), mainly contrast agents; and, 3) prevention of hypoglycemia.