ESR1 and neoplasm: The Memorial Sloan-Kettering Cancer Center (MSCC) created a nomogram using factors correlated with the tumor size, histologic type, nuclear grade, lymphovascular invasion, multifocality and estrogen receptor, thus screening a group of SLN-positive women who might benefit from the omission of ALND.3Several attempts have been made to reproduce and validate the MSCC nomogram, with conflicting results.17, 18