Our previous studies have revealed several hypoxia‐responsive genes, including vasodilator‐stimulated phosphoprotein (VASP), long non‐coding RNA (lncRNA) EIF3J‐AS1, tuftelin 1 (TUFT1), miR‐3677‐3p/miR‐3682‐3p, regulating HCC growth and metastasis.10, 11, 12, 13, 14. This evidence concerns the gene TUFT1 and hepatocellular carcinoma.