Interestingly, the expression of VEGF family showed a decreased tendency in the fibroblasts after PD stimulation; in contrast, the expression level of TGF‐β1 increased obviously, which was consistent with the hypothesis that the continuous activation of TGF‐β signaling pathway promotes the transformation of fibroblasts as appearing in the entire process of PF. Here, TGFB1 is linked to pemphigus foliaceus.