The prognostic value of GLUT1 has also been explored by Sharen et al., who found that a high level of GLUT1 expression was associated with a tumor size greater than 2 cm and with lymph node metastasis in patients with pancreatic cancer, and these features resulted in shorter overall survival.71 This evidence concerns the gene SLC2A1 and metastatic malignant neoplasm in the lymph nodes.