HADHA is a mitochondrial trifunctional enzyme specifically involved in the last three of the four reactions of long‐chain fatty acids beta‐oxidation pathway,56, 57, 58 and the acetylation levels of the K60, K129, and K569 of HDAHA were also downregulated in tumor tissues,7 which is consistent with our results (Table S6). Here, CXCL8 is linked to neoplasm.