Our qRT‐PCR results revealed that the expression levels of TNFSF10 (p < 0.01), ECM1 (p < 0.01), and RNF213 (p < 0.01) were significantly increased in advanced LUAD tumor cells, whereas the expression of SCGB3A2 (p < 0.01), SCGB3A1 (p < 0.01), and SFTPC (p < 0.01) was increased in early LUAD (Figure S6B and S6C). Here, ECM1 is linked to neoplasm.