MAPT and Alzheimer disease: Retinal changes in AD include the followings: (a) reduction in the number of retinal ganglion cells (RGC); (b) decreased thickness in the retinal nerve fiber layer (NFL); (c) decreased choroidal thickness in the foveal area; (d) visual field reduction; and (e) accumulation of tau and amyloid‐beta (Aβ) (Abulfadl et al., 2018).