An increase in norovirus-specific IgG and IgA has been reported after infection,48 with higher titers of preexisting salivary IgA being correlated with protection.33,45 Interestingly, when compared to norovirus-specific IgG antibodies, a higher proportion of IgA antibodies blocked the binding of norovirus to carbohydrates and exhibited a more potent blockade titer.49 IgAs were also shown to be superior to IgG in terms of murine norovirus (MNV) neutralization in vitro and protective function in vivo. This evidence concerns the gene CD79A and infection.