ACE and acute kidney injury: In multiple Cox regression analysis adjusted for age, sex, diabetes mellitus, hypertension, smoking, body mass index, hemoglobin, RDW-CV, eGFR, uric acid, CRP, proteinuria, AKI, medication usage at discharge such as statin and angiotensin II receptor blocker (ARB)/angiotensin-converting enzyme inhibitor (ACEI), low PNI was a significant risk factor for mortality (HR 0.98, CI 0.96–0.99, P = 0.003) (Table 3).