Univariate Cox regression analysis showed that LMNB2 expression, tumor node metastasis (TNM) stage, lymph node metastasis, tumor diameter, and depth of invasion are important prognostic factors affecting overall survival (OS) and disease-free survival (DFS) in patients with CRC (Additoonal File 3 Table S3). The gene discussed is LMNB2; the disease is metastatic malignant neoplasm in the lymph nodes.