Both short isoforms of WDPCP and RAB27B, which are induced by PRMT4, 5, and 7, promoted the proliferation of MCF7 cells, whereas the long isoform did so to a much lesser extent or even exhibited an opposite effect, thus linking aberrant splicing to cancer cell growth (Supplementary Fig. 7v–y). This evidence concerns the gene CARM1 and cancer.