MRC1 and neoplasm: Whereas there was no difference in total myeloid (CD45+ CD11b+), MDSC (CD11b+ Ly-6G+ Ly-6C+), or total macrophage (CD11b+ F4/80+) infiltration expressed as percentage of total cells, we observed an upward trend for specific macrophage populations (CD11b+ F4/80+ CD206+; CD11b+ F4/80+ PD-L1+) in scaffolds from tumor-bearing animals compared with controls, similar to the increase in macrophages in the tumor-bearing liver (Figs S1A and E and 1D).