It was known that some available markers for bladder cancer diagnosis mainly contained BTA Stat, BTA Trak, NMP22,6 Bladder Check, the ImmunoCyt test, UroVysion test, BLCA‐4, Survivin, and Microsatellite; however, their application to clinical practice still has many limitations due to their high false‐positive rate for high‐stage bladder cancer verification. The gene discussed is BIRC5; the disease is urinary bladder cancer.