On the other hand, the top 20 upregulated genes among metastatic tumors also included IRF1, CD74, FASLG, JAKMIP1, C1QA, IFNG, TNIP3, C1QB, APOL3, C1QC, CCL5, TRGV10, CRTAM and CD8A (Table S3 and Figure S3). Here, CCL5 is linked to metastatic neoplasm.