On the other hand, the top 20 upregulated genes among metastatic tumors also included IRF1, CD74, FASLG, JAKMIP1, C1QA, IFNG, TNIP3, C1QB, APOL3, C1QC, CCL5, TRGV10, CRTAM and CD8A (Table S3 and Figure S3). The gene discussed is CRTAM; the disease is metastatic neoplasm.