Other mineralization disorders may affect dentin, including multiple forms of osteogenesis imperfecta (OI), hypophosphatasia (HPP), and genetic/congenital forms of hypophosphatemic rickets.(48, 93, 94, 95, 96)Hyp mutant mice featuring mutations in phosphate‐regulating endopeptidase homolog X‐linked gene (Phex) represent a mouse model of X‐linked hypophosphatemia (XLH). This evidence concerns the gene PHEX and hypophosphatasia.