The Decipher gene signature could predict the BCR and metastasis in patients receiving postoperative radiotherapy (Den et al., 2014), and in patients following RP, it could also predict the early metastasis and even cancer-specific mortality (Erho et al., 2013; Ross et al., 2014; Klein et al., 2016; Nguyen et al., 2017; Karnes et al., 2018). This evidence concerns the gene BCR and cancer.