CXCL11 and neoplasm: We also found the upregulation of CXCL11 expression in tumor tissue compared with adjacent normal tissue (Figure 3H) in the COAD single-cell RNA-seq datasets GSE132465, and CXCL11 expression was positively correlated with PD-L1 (r = 0.78, P < 0.001; Figure 3I).