Tardelli et al. (2019) reported that inhibiting MAGL protects against liver injury and may be considered a potential therapy for sclerosing cholangitis. In addition, Xiang et al. (2018) reported that MAGL delays tumor progression by regulating activation of cannabinoid receptor 2-dependent macrophages. The latest study indicated that inhibiting MAGL protects against bone disease caused by primary bone cancer and bone metastasis (Marino et al., 2019). This evidence concerns the gene MGLL and bone cancer.