Mandelli et al. (2020) reported that basal type of bladder cancer contained a significantly higher density of CD66b+ tumor-associated neutrophils (TANs) compared to the luminal type, and a high density of TANs and T cells was significantly associated with a better outcome. However, Liu et al. (2018) found that elevated CD66b+ TAN was correlated with an advanced T-stage, a high grade, a worse recurrence-free survival within non-muscle invasive bladder cancer subgroup and a worse overall survival within all urothelial bladder cancer cases. This evidence concerns the gene CEACAM8 and urinary bladder cancer.