PDLIM7 and breast carcinoma: Our data showed clearly that E6/E7 of high-risk HPV type 16 can cooperate with LMP1 of EBV to enhance cell proliferation and deregulate cell cycle progression of MCF7, MDA-MB-231, and HNME cells; in addition, this cooperation stimulates colony formation of human breast cancer cells, but not in HNME cells, thus indicating its inability to provoke neoplastic transformation of human normal mammary cells.