PDLIM7 and breast carcinoma: We initially analyzed the proliferative ability of transduced cell lines in comparison with their wild-type cells using the MTT assay; our data revealed that E6/E7 and LMP1 alone enhance cell proliferation in breast cancer cell lines, whereas the co-presence of E6/E7 and LMP1 induces significant cell proliferation (5-fold, 3.4-fold, and 2-fold) in both breast cancer and normal mammary cells in comparison with cells expressing E6/E7 (2-fold, 1.4-fold, and 1.3-fold) or LPM1 (3-fold, 1.8-fold, and 1-fold) alone in MCF7, MDA-MB-231, and HNME, respectively, and in control cells (Figure 2).