IL15 and cancer: The expression of CD107a by NK cells also increased when cells were treated with either IL-15 or IL-15 combined with ADU-S100 analog (Figure 3E), and was also higher in PBMC-cancer cell co-cultures compared with PBMCs incubated without cancer cells, however, there was no significant differences in expression with IL-15 compared to the IL-15 and ADU-S100 combination.