FOXD2 and neoplasm: Related studies have shown that FOXD2-AS1 is upregulated in various malignancies, including gastric, lung, bladder, colorectal, etc., thus contributing to proliferation, migration, and invasion of tumor cells in various pathways (29), such as through their interaction with microRNA-185-5p (30); NRIR, also known as lncRNA-CMPK2, is a spliced, polyadenylated nuclear transcript induced by IFN in diverse cell types from human and mouse.