PIK3CD and acute lymphoblastic leukemia: Using B-ALL patient-derived long-term cultures, the effectiveness of dual inhibitors NVP-BEZ235 (dactolisib) and NVP-BGT226 was tested and compared with those of the pan-PI3K inhibitor NVP-BKM120, combined mTORC1/mTORC2 inhibitors Torin1, PP242, KU-0063794, and the allosteric mTORC1 inhibitor RAD001.