In addition, analysis of polyps revealed a correlation between CD26 levels and grade of dysplasia and the presence of advanced adenomas, with a 58.0% (95% CI: 46.5%-68.9%) sensitivity and 75.5% (95% CI: 68.5%-81.0%) specificity in detecting colorectal cancer and advanced adenomas. This evidence concerns the gene DPP4 and colorectal cancer.