In renal cell carcinoma, UCA1 upregulates Delta-like 4 (DLL4) expression by acting as a ceRNA of miR-182-5p, and induces the EMT process via the DLL4-mediated Notch pathway, which in turn promotes cell proliferation and migration, and inhibits apoptosis (11). Here, DLL4 is linked to hereditary clear cell renal cell carcinoma.