Recently, Wang et al. have revealed that the levels of growth differentiation factor 15 (GDF15) in the heart and plasma are elevated in a mice model of primary pediatric cardiomyopathy with secondary failure to thrive (FTT), and the plasma GDF15 levels are elevated in children with concomitant heart disease and FTT [139]. The gene discussed is GDF15; the disease is Failure to thrive.