In the coculture conditions allowing or preventing (transwell) direct cell-to-cell contact, untreated and TI-treated AS/ASCs similarly reduced proliferation of CD4+ (Figures 2(d)–2(f)) and CD8+ (Figures 3(d)–3(f)) T cells, while the inhibitory effect of HD/ASCs was even more potent in transwell than cell-to-cell contact cultures, and such differences were observed in the case of CD4+ (Figures 2(a)–2(c)) and CD8+ (Figures 3(a)–3(c)) T cells. Here, CD4 is linked to Huntington disease.