Similarly, Reis et al. [11] examined men and women aged 20 y and older using data from the 2003-2004 NHANES and found those with 25(OH)D ≥35 ng/ml had a 74% lower odds of prevalent MetS independent of confounders including calcium intake and PTH, and the association was unaffected by age or gender. This evidence concerns the gene PTH and metabolic syndrome.