GAS5 and central nervous system cancer: As the research on GAS5 going further, more and more studies have shown that lncRNA GAS5 is low-expressed in most of the tumor samples, such as glioma, non-small cell lung cancer, breast carcinoma, etc. As a tumor suppressor, GAS5 is involved in the regulation of tumor occurrence and progression (Cao et al., 2017; Gu et al., 2018; Liu et al., 2018).