No correlation was found for the frequencies of CD11c+ B cells and the age of the individual donors, the expression of Siglec-1 (CD169) on monocytes (as marker of the type I interferon signature) or the disease activity scores SLEDAI for SLE and ESSDAI for pSS, respectively (data not shown). The gene discussed is SIGLEC1; the disease is systemic lupus erythematosus.