Further analyses revealed a correlation between the frequencies of CD11c+ and CD21−CD27− B cells both from HD (r = 0.74, p = 0.0002), pSS (r = 0.60, p = 0.0013) and SLE patients (r = 0.80, p < 0.0001) (Figure 2C). Here, ITGAX is linked to systemic lupus erythematosus.