Additionally, 14 soluble factors (IL-1 β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12p70, IL-13, IL-17A, FGF, GM-CSF, G-CSF, and PDGF-BB), were undetectable in the CSF of patients with both PP-MS and SP-MS (data not shown). This evidence concerns the gene IL6 and myeloid sarcoma.