In particular, we found that chemokines, MCP-1 (CCL2), MIP-1 α (CCL3), MIP-1 β (CCL4), RANTES (CCL5), eotaxin (CCL11), IP-10 (CXCL10), and IL-8 (CXCL8), were expressed in the CSF of patients with both PP-MS and SP-MS. The gene discussed is CXCL8; the disease is myeloid sarcoma.