A total of 104 out of 198 patients performed a genetic screening: 2 patients with ILD presented a TACI mutation, as well as 3 controls, and 5 patients with CVID-ILD presented a CTLA4 mutation (3 with histologic diagnosis of GLILD, 1 with a clinical-radiologic diagnosis of uILD). Here, CTLA4 is linked to interstitial lung disease.