When lymphocytes subpopulations analysis was available, mean CD4/CD8 ratio (19 patients) was 2.23 (SD 1.93), median was 1.58 (IQ range 0.53–3.6); 5 patients presented a CD4/CD8 ratio >3.5, as per sarcoidosis diagnostic criteria (18) and 7 > 3.0; in 7 patients ratio was reduced (<1.4). The gene discussed is CD8A; the disease is sarcoidosis.