Regarding growth factors, high levels of HGF and VEGF were observed in serum during the acute phase of the neurological and non-neurological diseases, differing from the levels reported for infants with congenital neurological disease (46), but agreeing with results reported for patients with ZIKV (VEGF and G-CSF) when compared to non-infected individuals (25). This evidence concerns the gene HGF and nervous system disorder.