Under SCA subgroups, IL-1β can also be used to categorize StSt patients, when >0.43 pg/ml, or if <0.43 pg/ml, a further analysis contribute to identify VOC if IL-6 >2.66 pg/ml or CV if IL-6 ≤ 2.66 pg/ml (Figure 3E). Here, IL1B is linked to autosomal dominant cerebellar ataxia.