C4A and Huntington disease: Significantly higher levels of chemokines (CXCL8, CXCL10, CCL3, CCL4, CCL5), cytokines (IL-1β, IL-12p70, IL-17A, IL-10), growth factors (VEGF and GM-CSF) and anaphylatoxin C4a were found in SCA patients, when compared to the HD group, as shown in Figure 1.